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We introduce the Mindboggle dataset, the largest and most complete set of free, publicly accessible, manually labeled human brain images. To manually label the macroscopic anatomy in magnetic resonance images of healthy participants, we created a new cortical labeling protocol that relies on robust anatomical landmarks and minimal manual edits after initialization with automated labels. Given how difficult it is to label brains, the Mindboggle dataset is intended to serve as brain atlases for use in labeling other brains, as a normative dataset to establish morphometric variation in a healthy population for comparison against clinical populations, and contribute to the development, training, testing, and evaluation of automated registration and labeling algorithms. To this end, we also introduce benchmarks for the evaluation of such algorithms by comparing our manual labels with labels automatically generated by probabilistic and multi-atlas registration-based approaches. Labeling the macroscopic anatomy of the human brain is instrumental in educating biologists and clinicians, visualizing biomedical data, localizing brain data for identification and comparison, and perhaps most importantly, subdividing brain data for analysis.
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3D Images: Exploring the Human Brain | Live Science

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3D Images: Exploring the Human Brain

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